<International Circulation>:We are seeing changes in the endothelium that end up affecting high blood pressure and the formation of collagen that are happening indirectly because the endothelium is changing and causing a cascade of effects.
《国际循环》:我们发现内皮系统的改变能影响高血压和胶原的形成,这些都是间接发生的,因为内皮系统会发生改变并导致一系列的级联反应。
Prof. Alvolio : With the advent of molecular biology, these pathways are being identified and it is quite exciting to see if in fact like the endothelial was once thought to be a lining of the blood vessel and now it is an active part of the circulatory system. Similarly with arterial stiffness, the elasticity was thought to have been mainly related to blood pressure, but can this stiffness property be modified through these cellular and molecular processes. We’ve seen the effect salt and now we’re starting to understand some these mechanisms.
Alvolio教授:随着分子生物学的进展这些通路就会被发现,而且非常令人振奋的是能看到内皮曾经被认为只是血管的内层部分,而现在发现它还是循环系统的活性部分。和动脉僵硬度相似,动脉的弹性被认为主要和血压相关,但是还不知道这种僵硬度特性能否通过这些细胞和分子的过程被调节。我们已经发现了盐的作用,现在我们已经开始探索它导致动脉发生变化的一些机制。
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