手机网
关键词
首页>>正文

JUPITER试验:稳定型冠心病患者血清C-反应蛋白水平
[2010/12/6 16:23:40]
 全文(共1页)

    Saely CH, Rein P, Vonbank A, Drexel H.
Abstract
    BACKGROUND: The JUPITER trial has recently demonstrated an outstanding reduction of cardiovascular events by 20 mg rosuvastatin/day in subjects with high CRP who were apparently healthy at baseline. However, absence of atherosclerosis in JUPITER was based on the subjects’ history and not proven objectively.
    METHODS: To put the results of JUPITER in perspective, we evaluated serum CRP in a consecutive series of 703 statin-naïve Caucasian patients with angiographically proven stable CAD.
    RESULTS: From these stable CAD patients, only 69.2% met the ≥2.0 mg/l serum CRP inclusion criterion of the JUPITER trial. Median CRP [interquartile range] in our CAD patients was 3.3 [1.6-6.6] mg/l, which was significantly (p<0.001) lower than the median CRP in JUPITER (4.2 mg/l).
    CONCLUSIONS: Our results point to considerable subclinical atherosclerosis in the patients studied in JUPITER. The impressive results of that trial may not be generalizable to healthy populations all over the world.

 




 
更多热点
更多   心血管   相关搜索
声明:登陆《国际循环》手机网不收业务信息费,只产生运营商收取的上网流量费。
返回顶端| About Us | 客服中心 |收藏本站
WapURL手机网址(wap.icirculation.com)